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Role of pathology peer review in interpretation of the comet assay

When a comet assay, an increasingly popular in vivo genotoxicity test, shows a positive test result, interpretation of that response requires ruling out any confounding tissue site toxicity. Since the comet assay typically uses only two or three daily doses of test agent, precursor tissue changes in...

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Detalles Bibliográficos
Autores principales: Maronpot, Robert R., Hobbs, Cheryl A., Hayashi, Shim-mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077155/
https://www.ncbi.nlm.nih.gov/pubmed/30093784
http://dx.doi.org/10.1293/tox.2018-0019