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Mechanisms of oxidative stress-induced in vivo mutagenicity by potassium bromate and nitrofurantoin
Oxidative stress is well known as a key factor of chemical carcinogenesis. However, the actual role of oxidative stress in carcinogenesis, such as oxidative stress-related in vivo mutagenicity, remains unclear. It has been reported that 8-hydroxydeoxyguanosine (8-OHdG), an oxidized DNA lesion, might...
Autores principales: | Tsuchiya, Takuma, Kijima, Aki, Ishii, Yuji, Takasu, Shinji, Yokoo, Yuh, Nishikawa, Akiyoshi, Yanai, Tokuma, Umemura, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Toxicologic Pathology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077160/ https://www.ncbi.nlm.nih.gov/pubmed/30093787 http://dx.doi.org/10.1293/tox.2018-0024 |
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