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Potential Mechanisms Connecting Purine Metabolism and Cancer Therapy

Unrestricted cell proliferation is a hallmark of cancer. Purines are basic components of nucleotides in cell proliferation, thus impaired purine metabolism is associated with the progression of cancer. The de novo biosynthesis of purine depends on six enzymes to catalyze the conversion of phosphorib...

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Detalles Bibliográficos
Autores principales:	Yin, Jie, Ren, Wenkai, Huang, Xingguo, Deng, Jinping, Li, Tiejun, Yin, Yulong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077182/ https://www.ncbi.nlm.nih.gov/pubmed/30105018 http://dx.doi.org/10.3389/fimmu.2018.01697

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