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Notch Signaling Modulates Macrophage Polarization and Phagocytosis Through Direct Suppression of Signal Regulatory Protein α Expression

The Notch pathway plays critical roles in the development and functional modulation of myeloid cells. Previous studies have demonstrated that Notch activation promotes M1 polarization and phagocytosis of macrophages; however, the downstream molecular mechanisms mediating Notch signal remain elusive....

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Detalles Bibliográficos
Autores principales:	Lin, Yan, Zhao, Jun-Long, Zheng, Qi-Jun, Jiang, Xun, Tian, Jiao, Liang, Shi-Qian, Guo, Hong-Wei, Qin, Hong-Yan, Liang, Ying-Min, Han, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077186/ https://www.ncbi.nlm.nih.gov/pubmed/30105024 http://dx.doi.org/10.3389/fimmu.2018.01744

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