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Enhanced Immune Responses Conferring Cross-Protection by Skin Vaccination With a Tri-Component Influenza Vaccine Using a Microneedle Patch
Skin vaccination using biodegradable microneedle patch (MNP) technology in vaccine delivery is a promising strategy showing significant advantages over conventional flu shots. In this study, we developed an MNP encapsulating a 4M2e-tFliC fusion protein and two types of whole inactivated influenza vi...
Autores principales: | Zhu, Wandi, Li, Song, Wang, Chao, Yu, Guoying, Prausnitz, Mark R., Wang, Bao-Zhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077188/ https://www.ncbi.nlm.nih.gov/pubmed/30105019 http://dx.doi.org/10.3389/fimmu.2018.01705 |
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