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Increased iNKT17 Cell Frequency in the Intestine of Non-Obese Diabetic Mice Correlates With High Bacterioidales and Low Clostridiales Abundance

iNKT cells play different immune function depending on their cytokine-secretion phenotype. iNKT17 cells predominantly secrete IL-17 and have an effector and pathogenic role in the pathogenesis of autoimmune diseases such as type 1 diabetes (T1D). In line with this notion, non-obese diabetic (NOD) mi...

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Detalles Bibliográficos
Autores principales: De Giorgi, Lorena, Sorini, Chiara, Cosorich, Ilaria, Ferrarese, Roberto, Canducci, Filippo, Falcone, Marika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077215/
https://www.ncbi.nlm.nih.gov/pubmed/30105027
http://dx.doi.org/10.3389/fimmu.2018.01752