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Loss of RANKL in osteocytes dramatically increases cancellous bone mass in the osteogenesis imperfecta mouse (oim)

Osteogenesis imperfecta (OI) is characterized by osteopenia and bone fragility, and OI patients during growth often exhibit high bone turnover with the net result of low bone mass. Recent evidence shows that osteocytes significantly affect bone remodeling under physiological and pathological conditi...

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Detalles Bibliográficos
Autores principales: Zimmerman, Sarah M., Heard-Lipsmeyer, Melissa E., Dimori, Milena, Thostenson, Jeff D., Mannen, Erin M., O'Brien, Charles A., Morello, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077550/
https://www.ncbi.nlm.nih.gov/pubmed/30105276
http://dx.doi.org/10.1016/j.bonr.2018.06.008

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