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Loss of RANKL in osteocytes dramatically increases cancellous bone mass in the osteogenesis imperfecta mouse (oim)
Osteogenesis imperfecta (OI) is characterized by osteopenia and bone fragility, and OI patients during growth often exhibit high bone turnover with the net result of low bone mass. Recent evidence shows that osteocytes significantly affect bone remodeling under physiological and pathological conditi...
Autores principales: | Zimmerman, Sarah M., Heard-Lipsmeyer, Melissa E., Dimori, Milena, Thostenson, Jeff D., Mannen, Erin M., O'Brien, Charles A., Morello, Roy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077550/ https://www.ncbi.nlm.nih.gov/pubmed/30105276 http://dx.doi.org/10.1016/j.bonr.2018.06.008 |
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