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A Long-Term Study of a Lipid-Buprenorphine Implant in Rats
Animal models to study opiates are of growing interest. We have examined the short-term safety of buprenorphine implants in Fischer F344/NTac rats treated with excess doses of a cholesterol-triglyceride suspension of buprenorphine. A single injection of 0.65 mg/kg afforded clinically significant blo...
Autores principales: | Guarnieri, Michael, Brayton, Cory, Tyler, Betty M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077592/ https://www.ncbi.nlm.nih.gov/pubmed/30112418 http://dx.doi.org/10.1155/2018/2616152 |
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