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A Long-Term Study of a Lipid-Buprenorphine Implant in Rats

Animal models to study opiates are of growing interest. We have examined the short-term safety of buprenorphine implants in Fischer F344/NTac rats treated with excess doses of a cholesterol-triglyceride suspension of buprenorphine. A single injection of 0.65 mg/kg afforded clinically significant blo...

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Detalles Bibliográficos
Autores principales: Guarnieri, Michael, Brayton, Cory, Tyler, Betty M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077592/
https://www.ncbi.nlm.nih.gov/pubmed/30112418
http://dx.doi.org/10.1155/2018/2616152

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