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A New Surgical Method of U-Shaped Myometrial Excavation and Modified Suture Approach with Uterus Preservation for Diffuse Adenomyosis

OBJECTIVE: To evaluate the feasibility, safety, and efficacy of a new surgical method of U-shaped myometrial excavation and modified suture approach with uterus preservation for diffuse adenomyosis. METHODS: From January 2012 to December 2014, 198 patients with diffuse adenomyosis were surgically tr...

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Autores principales: Jun-Min, Xie, Kun-Peng, Zhu, Yin-Kai, Zhao, Ya-Qin, Zhang, Xiao-Fan, Fan, Xiao-Yu, Zhu, Li, Wei, Bin, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077673/
https://www.ncbi.nlm.nih.gov/pubmed/30112362
http://dx.doi.org/10.1155/2018/1657237
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author Jun-Min, Xie
Kun-Peng, Zhu
Yin-Kai, Zhao
Ya-Qin, Zhang
Xiao-Fan, Fan
Xiao-Yu, Zhu
Li, Wei
Bin, Wang
author_facet Jun-Min, Xie
Kun-Peng, Zhu
Yin-Kai, Zhao
Ya-Qin, Zhang
Xiao-Fan, Fan
Xiao-Yu, Zhu
Li, Wei
Bin, Wang
author_sort Jun-Min, Xie
collection PubMed
description OBJECTIVE: To evaluate the feasibility, safety, and efficacy of a new surgical method of U-shaped myometrial excavation and modified suture approach with uterus preservation for diffuse adenomyosis. METHODS: From January 2012 to December 2014, 198 patients with diffuse adenomyosis were surgically treated using this novel procedure in Zhengzhou Hua-Shan Hospital. Degree of dysmenorrhea, menstrual blood volume, serum CA 125, and uterine size before and at 1 month, 3 months, 6 months, 12 months, and 24 months after surgery were compared. RESULTS: Postoperatively, VAS score of dysmenorrhea, menstrual blood volume, serum CA 125 level, and uterine size significantly decreased at 1 month, 3 months, 6 months, 12 months, and 24 months from presurgical levels (all p < .001), but there were no differences at the follow-up time points. Two patients recurred at 18 months and 23 months after surgery, but both recovered after repeat surgery. Interestingly, 2 other patients recrudesced at 10 months and 12 months after surgery. In addition, only one patient was found to have a postoperative anaemia with fever, conservatively managed without surgery. CONCLUSION: U-shaped myometrial excavation and modified suture approach with uterus preservation is a safe and feasible surgical approach to treat diffuse adenomyosis, with favourable outcomes.
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spelling pubmed-60776732018-08-15 A New Surgical Method of U-Shaped Myometrial Excavation and Modified Suture Approach with Uterus Preservation for Diffuse Adenomyosis Jun-Min, Xie Kun-Peng, Zhu Yin-Kai, Zhao Ya-Qin, Zhang Xiao-Fan, Fan Xiao-Yu, Zhu Li, Wei Bin, Wang Biomed Res Int Clinical Study OBJECTIVE: To evaluate the feasibility, safety, and efficacy of a new surgical method of U-shaped myometrial excavation and modified suture approach with uterus preservation for diffuse adenomyosis. METHODS: From January 2012 to December 2014, 198 patients with diffuse adenomyosis were surgically treated using this novel procedure in Zhengzhou Hua-Shan Hospital. Degree of dysmenorrhea, menstrual blood volume, serum CA 125, and uterine size before and at 1 month, 3 months, 6 months, 12 months, and 24 months after surgery were compared. RESULTS: Postoperatively, VAS score of dysmenorrhea, menstrual blood volume, serum CA 125 level, and uterine size significantly decreased at 1 month, 3 months, 6 months, 12 months, and 24 months from presurgical levels (all p < .001), but there were no differences at the follow-up time points. Two patients recurred at 18 months and 23 months after surgery, but both recovered after repeat surgery. Interestingly, 2 other patients recrudesced at 10 months and 12 months after surgery. In addition, only one patient was found to have a postoperative anaemia with fever, conservatively managed without surgery. CONCLUSION: U-shaped myometrial excavation and modified suture approach with uterus preservation is a safe and feasible surgical approach to treat diffuse adenomyosis, with favourable outcomes. Hindawi 2018-07-09 /pmc/articles/PMC6077673/ /pubmed/30112362 http://dx.doi.org/10.1155/2018/1657237 Text en Copyright © 2018 Xie Jun-Min et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Jun-Min, Xie
Kun-Peng, Zhu
Yin-Kai, Zhao
Ya-Qin, Zhang
Xiao-Fan, Fan
Xiao-Yu, Zhu
Li, Wei
Bin, Wang
A New Surgical Method of U-Shaped Myometrial Excavation and Modified Suture Approach with Uterus Preservation for Diffuse Adenomyosis
title A New Surgical Method of U-Shaped Myometrial Excavation and Modified Suture Approach with Uterus Preservation for Diffuse Adenomyosis
title_full A New Surgical Method of U-Shaped Myometrial Excavation and Modified Suture Approach with Uterus Preservation for Diffuse Adenomyosis
title_fullStr A New Surgical Method of U-Shaped Myometrial Excavation and Modified Suture Approach with Uterus Preservation for Diffuse Adenomyosis
title_full_unstemmed A New Surgical Method of U-Shaped Myometrial Excavation and Modified Suture Approach with Uterus Preservation for Diffuse Adenomyosis
title_short A New Surgical Method of U-Shaped Myometrial Excavation and Modified Suture Approach with Uterus Preservation for Diffuse Adenomyosis
title_sort new surgical method of u-shaped myometrial excavation and modified suture approach with uterus preservation for diffuse adenomyosis
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077673/
https://www.ncbi.nlm.nih.gov/pubmed/30112362
http://dx.doi.org/10.1155/2018/1657237
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