Cargando…

OCT4 Potentiates Radio-Resistance and Migration Activity of Rectal Cancer Cells by Improving Epithelial-Mesenchymal Transition in a ZEB1 Dependent Manner

Radiotherapy is an important strategy for rectal cancer patient treatment. However, the efficiency of radiation is usually poor, especially in patients with advanced stage rectal cancer due to the radio-resistance developed. At the present study, OCT4 was found to play a critical role in radio-resis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shao, Minghai, Bi, Tienan, Ding, Wenxiu, Yu, Changhui, Jiang, Caiping, Yang, Haihua, Sun, Xinchen, Yang, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077687/ https://www.ncbi.nlm.nih.gov/pubmed/30112378 http://dx.doi.org/10.1155/2018/3424956

Ejemplares similares

Capecitabine inhibits epithelial-to-mesenchymal transition and proliferation of colorectal cancer cells by mediating the RANK/RANKL pathway
por: Shao, Minghai, et al.
Publicado: (2022)

MTBP promotes migration and invasion by regulation of ZEB2-mediated epithelial–mesenchymal transition in lung cancer cells
por: Pan, Bo, et al.
Publicado: (2018)

miR-101 suppresses the epithelial-to-mesenchymal transition by targeting ZEB1 and ZEB2 in ovarian carcinoma
por: GUO, FEI, et al.
Publicado: (2014)

p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
por: Kim, Taewan, et al.
Publicado: (2011)

The role of epithelial–mesenchymal transition drivers ZEB1 and ZEB2 in mediating docetaxel‐resistant prostate cancer
por: Hanrahan, Karen, et al.
Publicado: (2017)

MTBP promotes migration and invasion by regulation of ZEB2-mediated epithelial–mesenchymal transition in lung cancer cells [Corrigendum]
Publicado: (2018)

Polydatin inhibits ZEB1‐invoked epithelial‐mesenchymal transition in fructose‐induced liver fibrosis
por: Zhao, Xiaojuan, et al.
Publicado: (2020)

LDH-Apromotes epithelial–mesenchymal transition by upregulating ZEB2 in intestinal-type gastric cancer
por: Zhang, Yongjie, et al.
Publicado: (2018)

Overexpression of ZEB2‐AS1 promotes epithelial‐to‐mesenchymal transition and metastasis by stabilizing ZEB2 mRNA in head neck squamous cell carcinoma
por: Diao, Pengfei, et al.
Publicado: (2019)

Long non-coding RNA ZEB1-AS1 promotes cell invasion and epithelial to mesenchymal transition through inducing ZEB1 expression in cervical cancer
por: Cheng, Rongjie, et al.
Publicado: (2018)

TMPRSS2/ERG Promotes Epithelial to Mesenchymal Transition through the ZEB1/ZEB2 Axis in a Prostate Cancer Model
por: Leshem, Orit, et al.
Publicado: (2011)

Long non‐coding RNA ZEB2‐AS1 promotes the proliferation, metastasis and epithelial mesenchymal transition in triple‐negative breast cancer by epigenetically activating ZEB2
por: Zhang, Guoxin, et al.
Publicado: (2019)

Methyl vanillate for inhibiting the proliferation, migration, and epithelial-mesenchymal transition of ovarian cancer cells via the ZEB2/Snail signaling pathway
por: Wang, Ling, et al.
Publicado: (2023)

Reversal of transforming growth factor-β induced epithelial-to-mesenchymal transition and the ZEB proteins
por: Das, Shreyasi, et al.
Publicado: (2012)

Role and prognostic significance of the epithelial-mesenchymal transition factor ZEB2 in ovarian cancer
por: Prislei, Silvia, et al.
Publicado: (2015)

Ovol2 induces mesenchymal–epithelial transition via targeting ZEB1 in osteosarcoma
por: Liu, Jijun, et al.
Publicado: (2018)

Prognostic Role of Epithelial-Mesenchymal Transition Markers “E-Cadherin, β-Catenin, ZEB1, ZEB2 and p63” in Bladder Carcinoma
por: Moussa, Rabab Ahmed, et al.
Publicado: (2019)

MicroRNA-212-3p inhibits paclitaxel resistance through regulating epithelial-mesenchymal transition, migration and invasion by targeting ZEB2 in human hepatocellular carcinoma
por: Yang, Jianyu, et al.
Publicado: (2020)

FOXO1 inhibits the invasion and metastasis of hepatocellular carcinoma by reversing ZEB2-induced epithelial-mesenchymal transition
por: Dong, Tianxiu, et al.
Publicado: (2016)

CHFR promotes the migration of human gastric cancer cells by inducing epithelial-to-mesenchymal transition in a HDAC1-dependent manner
por: Yang, Shangwen, et al.
Publicado: (2019)

Retraction statement: MicroRNA‐431 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the ZEB1‐mediated epithelial–mesenchymal transition
Publicado: (2022)

Factors Affecting the Survival of Patients with Oligometastatic Non-Small-Cell Lung Cancer: A Meta-Analysis
por: Shi, Yu, et al.
Publicado: (2019)

Gastric Cancer Extracellular Vesicles Tune the Migration and Invasion of Epithelial and Mesenchymal Cells in a Histotype-Dependent Manner
por: Rocha, Sara, et al.
Publicado: (2019)

Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway
por: Das, Shreyas, et al.
Publicado: (2009)

Helicobacter pylori Initiates a Mesenchymal Transition through ZEB1 in Gastric Epithelial Cells
por: Baud, Jessica, et al.
Publicado: (2013)

Effect of AKT inhibition on epithelial-mesenchymal transition and ZEB1-potentiated radiotherapy in nasopharyngeal carcinoma
por: CHEN, WEIGUO, et al.
Publicado: (2013)

FLASH protects ZEB1 from degradation and supports cancer cells' epithelial-to-mesenchymal transition
por: Abshire, C F, et al.
Publicado: (2016)

RAE1 mediated ZEB1 expression promotes epithelial–mesenchymal transition in breast cancer
por: Oh, Ji Hoon, et al.
Publicado: (2019)

Human Schlafen 5 regulates reversible epithelial and mesenchymal transitions in breast cancer by suppression of ZEB1 transcription
por: Wan, Guoqing, et al.
Publicado: (2020)

Prognostic value of association of OCT4 with LEF1 expression in esophageal squamous cell carcinoma and their impact on epithelial‐mesenchymal transition, invasion, and migration
por: Zhao, Yue, et al.
Publicado: (2018)

Cardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent manner
por: Gladka, Monika M., et al.
Publicado: (2021)

Zeb1 Is a Potential Regulator of Six2 in the Proliferation, Apoptosis and Migration of Metanephric Mesenchyme Cells
por: Gu, Yuping, et al.
Publicado: (2016)

Tumor suppressor DCAF15 inhibits epithelial-mesenchymal transition by targeting ZEB1 for proteasomal degradation in hepatocellular carcinoma
por: Dong, Xiao, et al.
Publicado: (2021)

LINC01296/miR-141-3p/ZEB1-ZEB2 axis promotes tumor metastasis via enhancing epithelial-mesenchymal transition process
por: Sun, Zhenqiang, et al.
Publicado: (2021)

Glyceollin I Reverses Epithelial to Mesenchymal Transition in Letrozole Resistant Breast Cancer through ZEB1
por: Carriere, Patrick P., et al.
Publicado: (2015)

HOXD9 promotes epithelial–mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma
por: Lv, Xiupeng, et al.
Publicado: (2015)

ZEB1 Promotes Oxaliplatin Resistance through the Induction of Epithelial - Mesenchymal Transition in Colon Cancer Cells
por: Guo, Cao, et al.
Publicado: (2017)

Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition
por: Singh, Shalini, et al.
Publicado: (2016)

PARK2 negatively regulates the metastasis and epithelial-mesenchymal transition of glioblastoma cells via ZEB1
por: Wang, Haiyang, et al.
Publicado: (2017)

MTA1, a Target of Resveratrol, Promotes Epithelial-Mesenchymal Transition of Endometriosis via ZEB2
por: Kong, Xiangyi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_p8vutobqqmpa20hvni3urlqt1c