Phosphodiesterase 2 inhibition preferentially promotes NO/guanylyl cyclase/cGMP signaling to reverse the development of heart failure

Heart failure (HF) is a shared manifestation of several cardiovascular pathologies, including hypertension and myocardial infarction, and a limited repertoire of treatment modalities entails that the associated morbidity and mortality remain high. Impaired nitric oxide (NO)/guanylyl cyclase (GC)/cyc...

Descripción completa

Detalles Bibliográficos
Autores principales: Baliga, Reshma S., Preedy, Michael E. J., Dukinfield, Matthew S., Chu, Sandy M., Aubdool, Aisah A., Bubb, Kristen J., Moyes, Amie J., Tones, Michael A., Hobbs, Adrian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077693/
https://www.ncbi.nlm.nih.gov/pubmed/30012589
http://dx.doi.org/10.1073/pnas.1800996115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077693/
https://www.ncbi.nlm.nih.gov/pubmed/30012589
http://dx.doi.org/10.1073/pnas.1800996115

Ejemplares similares