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Qualified Biolayer Interferometry Avidity Measurements Distinguish the Heterogeneity of Antibody Interactions with Plasmodium falciparum Circumsporozoite Protein Antigens
Ab avidity is a measure of the overall strength of Ab–Ag interactions and hence is important for understanding the functional efficiency of Abs. In vaccine evaluations, Ab avidity measurements can provide insights into immune correlates of protection and generate hypotheses regarding mechanisms of p...
Autores principales: | Dennison, S. Moses, Reichartz, Matthew, Seaton, Kelly E., Dutta, Sheetij, Wille-Reece, Ulrike, Hill, Adrian V. S., Ewer, Katie J., Rountree, Wes, Sarzotti-Kelsoe, Marcella, Ozaki, Daniel A., Alam, S. Munir, Tomaras, Georgia D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077849/ https://www.ncbi.nlm.nih.gov/pubmed/30006374 http://dx.doi.org/10.4049/jimmunol.1800323 |
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