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Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations
The medial prefrontal cortex is involved in the process of sensory discrimination. In this study, we examined the local field potential activity response to the different stages of pain in the prelimbic cortex (PrL) which is a sub-region of the medial prefrontal cortex. Recent studies revealed exten...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077887/ https://www.ncbi.nlm.nih.gov/pubmed/29902945 http://dx.doi.org/10.1177/1744806918785686 |
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author | Fu, Bo Wen, Shao-nan Wang, Bin Wang, Kun Zhang, Ji-yan Liu, Shao-jun |
author_facet | Fu, Bo Wen, Shao-nan Wang, Bin Wang, Kun Zhang, Ji-yan Liu, Shao-jun |
author_sort | Fu, Bo |
collection | PubMed |
description | The medial prefrontal cortex is involved in the process of sensory discrimination. In this study, we examined the local field potential activity response to the different stages of pain in the prelimbic cortex (PrL) which is a sub-region of the medial prefrontal cortex. Recent studies revealed extensive information about neural oscillations, but there is limited information on the local field potential profiles for acute or chronic pain, particularly in freely moving animals. This study showed that acute mechanical pain increases alpha oscillation and decreases beta and gamma oscillations before spared nerve injury surgery. Delta oscillation was decreased by chronic pain and gamma oscillation varied with time. However, acute mechanical pain stimulus had no effects on local field potential in rats under mechanical allodynia. Together, our findings provide novel insights into the role of medial prefrontal cortex local field potential activity response to pain stimulus. |
format | Online Article Text |
id | pubmed-6077887 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-60778872018-08-08 Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations Fu, Bo Wen, Shao-nan Wang, Bin Wang, Kun Zhang, Ji-yan Liu, Shao-jun Mol Pain Short Report The medial prefrontal cortex is involved in the process of sensory discrimination. In this study, we examined the local field potential activity response to the different stages of pain in the prelimbic cortex (PrL) which is a sub-region of the medial prefrontal cortex. Recent studies revealed extensive information about neural oscillations, but there is limited information on the local field potential profiles for acute or chronic pain, particularly in freely moving animals. This study showed that acute mechanical pain increases alpha oscillation and decreases beta and gamma oscillations before spared nerve injury surgery. Delta oscillation was decreased by chronic pain and gamma oscillation varied with time. However, acute mechanical pain stimulus had no effects on local field potential in rats under mechanical allodynia. Together, our findings provide novel insights into the role of medial prefrontal cortex local field potential activity response to pain stimulus. SAGE Publications 2018-06-14 /pmc/articles/PMC6077887/ /pubmed/29902945 http://dx.doi.org/10.1177/1744806918785686 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Short Report Fu, Bo Wen, Shao-nan Wang, Bin Wang, Kun Zhang, Ji-yan Liu, Shao-jun Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations |
title | Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations |
title_full | Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations |
title_fullStr | Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations |
title_full_unstemmed | Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations |
title_short | Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations |
title_sort | acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations |
topic | Short Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077887/ https://www.ncbi.nlm.nih.gov/pubmed/29902945 http://dx.doi.org/10.1177/1744806918785686 |
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