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Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations

The medial prefrontal cortex is involved in the process of sensory discrimination. In this study, we examined the local field potential activity response to the different stages of pain in the prelimbic cortex (PrL) which is a sub-region of the medial prefrontal cortex. Recent studies revealed exten...

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Autores principales: Fu, Bo, Wen, Shao-nan, Wang, Bin, Wang, Kun, Zhang, Ji-yan, Liu, Shao-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077887/
https://www.ncbi.nlm.nih.gov/pubmed/29902945
http://dx.doi.org/10.1177/1744806918785686
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author Fu, Bo
Wen, Shao-nan
Wang, Bin
Wang, Kun
Zhang, Ji-yan
Liu, Shao-jun
author_facet Fu, Bo
Wen, Shao-nan
Wang, Bin
Wang, Kun
Zhang, Ji-yan
Liu, Shao-jun
author_sort Fu, Bo
collection PubMed
description The medial prefrontal cortex is involved in the process of sensory discrimination. In this study, we examined the local field potential activity response to the different stages of pain in the prelimbic cortex (PrL) which is a sub-region of the medial prefrontal cortex. Recent studies revealed extensive information about neural oscillations, but there is limited information on the local field potential profiles for acute or chronic pain, particularly in freely moving animals. This study showed that acute mechanical pain increases alpha oscillation and decreases beta and gamma oscillations before spared nerve injury surgery. Delta oscillation was decreased by chronic pain and gamma oscillation varied with time. However, acute mechanical pain stimulus had no effects on local field potential in rats under mechanical allodynia. Together, our findings provide novel insights into the role of medial prefrontal cortex local field potential activity response to pain stimulus.
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spelling pubmed-60778872018-08-08 Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations Fu, Bo Wen, Shao-nan Wang, Bin Wang, Kun Zhang, Ji-yan Liu, Shao-jun Mol Pain Short Report The medial prefrontal cortex is involved in the process of sensory discrimination. In this study, we examined the local field potential activity response to the different stages of pain in the prelimbic cortex (PrL) which is a sub-region of the medial prefrontal cortex. Recent studies revealed extensive information about neural oscillations, but there is limited information on the local field potential profiles for acute or chronic pain, particularly in freely moving animals. This study showed that acute mechanical pain increases alpha oscillation and decreases beta and gamma oscillations before spared nerve injury surgery. Delta oscillation was decreased by chronic pain and gamma oscillation varied with time. However, acute mechanical pain stimulus had no effects on local field potential in rats under mechanical allodynia. Together, our findings provide novel insights into the role of medial prefrontal cortex local field potential activity response to pain stimulus. SAGE Publications 2018-06-14 /pmc/articles/PMC6077887/ /pubmed/29902945 http://dx.doi.org/10.1177/1744806918785686 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Short Report
Fu, Bo
Wen, Shao-nan
Wang, Bin
Wang, Kun
Zhang, Ji-yan
Liu, Shao-jun
Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations
title Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations
title_full Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations
title_fullStr Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations
title_full_unstemmed Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations
title_short Acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations
title_sort acute and chronic pain affects local field potential of the medial prefrontal cortex in different band neural oscillations
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077887/
https://www.ncbi.nlm.nih.gov/pubmed/29902945
http://dx.doi.org/10.1177/1744806918785686
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