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Dimethyl fumarate improves white matter function following severe hypoperfusion: Involvement of microglia/macrophages and inflammatory mediators

The brain’s white matter is highly vulnerable to reductions in cerebral blood flow via mechanisms that may involve elevated microgliosis and pro-inflammatory pathways. In the present study, the effects of severe cerebral hypoperfusion were investigated on white matter function and inflammation. Male...

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Detalles Bibliográficos
Autores principales: Fowler, Jill H, McQueen, Jamie, Holland, Philip R, Manso, Yasmina, Marangoni, Martina, Scott, Fiona, Chisholm, Emma, Scannevin, Robert H, Hardingham, Giles E, Horsburgh, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077928/
https://www.ncbi.nlm.nih.gov/pubmed/28606007
http://dx.doi.org/10.1177/0271678X17713105