A k-mer based transcriptomics approach for antisense drug discovery targeting the Ewing’s family of tumors

Ewing’s sarcoma treatment failures are associated with high mortality indicating a need for new therapeutic approaches. We used a k-mer counting approach to identify cancer-specific mRNA transcripts in 3 Ewing’s Family Tumor (EFT) cell lines not found in the normal human transcriptome. Phosphorodiam...

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Detalles Bibliográficos
Autores principales: Annalora, Andrew J., O’Neil, Shawn, Bushman, Jeremy D., Summerton, James E., Marcus, Craig B., Iversen, Patrick L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078127/
https://www.ncbi.nlm.nih.gov/pubmed/30093970
http://dx.doi.org/10.18632/oncotarget.25736

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