Zafirlukast in combination with pseudohypericin attenuates spinal cord injury and motor function in experimental mice

BACKGROUND: Biosynthesis of leukotriene (LT) by arachidonic acid involves 5-lipoxygenase (5-LO) as an important precursor. Here, we evaluated the role of pseudohypericin (PHP) for its postulated 5-LO inhibitory activity along with a Cys-LT receptor antagonist zafirlukast (ZFL) against inflammatory r...

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Detalles Bibliográficos
Autores principales: Chen, Xiao-Gang, Hua, Fu, Wang, Shou-Guo, Xu, Yong-Yi, Yue, Hai-Tao, Sun, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078184/
https://www.ncbi.nlm.nih.gov/pubmed/30122897
http://dx.doi.org/10.2147/DDDT.S154814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078184/
https://www.ncbi.nlm.nih.gov/pubmed/30122897
http://dx.doi.org/10.2147/DDDT.S154814

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