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Zafirlukast in combination with pseudohypericin attenuates spinal cord injury and motor function in experimental mice

BACKGROUND: Biosynthesis of leukotriene (LT) by arachidonic acid involves 5-lipoxygenase (5-LO) as an important precursor. Here, we evaluated the role of pseudohypericin (PHP) for its postulated 5-LO inhibitory activity along with a Cys-LT receptor antagonist zafirlukast (ZFL) against inflammatory r...

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Detalles Bibliográficos
Autores principales:	Chen, Xiao-Gang, Hua, Fu, Wang, Shou-Guo, Xu, Yong-Yi, Yue, Hai-Tao, Sun, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078184/ https://www.ncbi.nlm.nih.gov/pubmed/30122897 http://dx.doi.org/10.2147/DDDT.S154814

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