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Comparison of biosimilar filgrastim with a reference product: pharmacokinetics, pharmacodynamics, and safety profiles in healthy volunteers

PURPOSE: Filgrastim, a granulocyte-colony stimulating factor, is used to treat patients with neutropenia, including neutropenic fever. Leucostim(®) is a recombinant filgrastim product tested for biosimilarity with its reference product, Neupogen(®). We conducted a comparative clinical trial of the 2...

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Detalles Bibliográficos
Autores principales:	Choi, Chungam, Yoo, Byung Won, Kim, Choon Ok, Hong, Taegon, Jin, Byung Hak, Seo, Kwang-Seok, Jang, Ja Yun, Park, Min Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Clinical Trial Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078186/ https://www.ncbi.nlm.nih.gov/pubmed/30122896 http://dx.doi.org/10.2147/DDDT.S158277

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