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Interaction between the cellular E3 ubiquitin ligase SIAH-1 and the viral immediate-early protein ICP0 enables efficient replication of Herpes Simplex Virus type 2 in vivo

Herpes Simplex Virus type 2 (HSV-2) is a neurotropic human pathogen. Upon de novo infection, the viral infected cell protein 0 (ICP0) is immediately expressed and interacts with various cellular components during the viral replication cycle. ICP0 is a multifunctional regulatory protein that has been...

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Detalles Bibliográficos
Autores principales:	Czechowicz, Julia S., Nagel, Claus-Henning, Voges, Maike, Spohn, Michael, Eibl, Martha M., Hauber, Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078308/ https://www.ncbi.nlm.nih.gov/pubmed/30080903 http://dx.doi.org/10.1371/journal.pone.0201880

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