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Formation of the sacrum requires down-regulation of sonic hedgehog signaling in the sacral intervertebral discs
In humans, the sacrum forms an important component of the pelvic arch, and it transfers the weight of the body to the lower limbs. The sacrum is formed by collapse of the intervertebral discs (IVDs) between the five sacral vertebrae during childhood, and their fusion to form a single bone. We show t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078355/ https://www.ncbi.nlm.nih.gov/pubmed/29784673 http://dx.doi.org/10.1242/bio.035592 |