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Formation of the sacrum requires down-regulation of sonic hedgehog signaling in the sacral intervertebral discs

In humans, the sacrum forms an important component of the pelvic arch, and it transfers the weight of the body to the lower limbs. The sacrum is formed by collapse of the intervertebral discs (IVDs) between the five sacral vertebrae during childhood, and their fusion to form a single bone. We show t...

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Detalles Bibliográficos
Autores principales: Bonavita, Raffaella, Vincent, Kathleen, Pinelli, Robert, Dahia, Chitra Lekha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078355/
https://www.ncbi.nlm.nih.gov/pubmed/29784673
http://dx.doi.org/10.1242/bio.035592

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