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Early Assessment of Right Ventricular Function in Systemic Lupus Erythematosus Patients using Strain and Strain Rate Imaging
BACKGROUND: Right ventricular function is a crucial factor of the prognosis of systemic lupus erythematosus (SLE). OBJECTIVES: To evaluate the right ventricular function in SLE patients with different degrees of pulmonary hypertension (PH) by strain and strain rate imaging. METHODS: A total of 102 S...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Cardiologia - SBC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078377/ https://www.ncbi.nlm.nih.gov/pubmed/29898016 http://dx.doi.org/10.5935/abc.20180091 |
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author | Luo, Runlan Cui, Hongyan Huang, Dongmei Sun, Lihua Song, Shengda Sun, Mengyao Li, Guangsen |
author_facet | Luo, Runlan Cui, Hongyan Huang, Dongmei Sun, Lihua Song, Shengda Sun, Mengyao Li, Guangsen |
author_sort | Luo, Runlan |
collection | PubMed |
description | BACKGROUND: Right ventricular function is a crucial factor of the prognosis of systemic lupus erythematosus (SLE). OBJECTIVES: To evaluate the right ventricular function in SLE patients with different degrees of pulmonary hypertension (PH) by strain and strain rate imaging. METHODS: A total of 102 SLE patients and 30 healthy volunteers were studied between October 2015 and May 2016. Patients were divided into three groups according to pulmonary artery systolic pressure (PASP) estimated by echocardiography: group control (A); PASP ≤ 30 mmHg (group B, n = 37); PASP 30-50 mmHg (mild PH; group C, n = 34); and PASP ≥ 50 mmHg (moderate-to-severe PH; group D, n = 31). Longitudinal peak systolic strain (ε) and strain rate (SR), including systolic strain rate (SRs), early diastolic strain rate (SRe) and late diastolic strain rate (SRa) were measured in the basal, middle and apical segments of the right ventricular free wall in participants by two-dimensional speckle tracking echocardiography (2D-STE) from the apical four-chamber view. A p < 0.05 was set for statistical significance. RESULTS: The parameters of ε, SRs, SRe, and SRa were significantly decreased in groups C and D compared with groups A and B. The ε of each segments was significantly lower in group D than in group C, while there were no differences in SRs, SRe and SRa between groups C and D. CONCLUSIONS: Strain and strain rate imaging could early detect the right ventricular dysfunction in SLE patients with PH, and provide important value for clinical therapy and prognosis of these patients. |
format | Online Article Text |
id | pubmed-6078377 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Sociedade Brasileira de Cardiologia - SBC |
record_format | MEDLINE/PubMed |
spelling | pubmed-60783772018-08-16 Early Assessment of Right Ventricular Function in Systemic Lupus Erythematosus Patients using Strain and Strain Rate Imaging Luo, Runlan Cui, Hongyan Huang, Dongmei Sun, Lihua Song, Shengda Sun, Mengyao Li, Guangsen Arq Bras Cardiol Original Article BACKGROUND: Right ventricular function is a crucial factor of the prognosis of systemic lupus erythematosus (SLE). OBJECTIVES: To evaluate the right ventricular function in SLE patients with different degrees of pulmonary hypertension (PH) by strain and strain rate imaging. METHODS: A total of 102 SLE patients and 30 healthy volunteers were studied between October 2015 and May 2016. Patients were divided into three groups according to pulmonary artery systolic pressure (PASP) estimated by echocardiography: group control (A); PASP ≤ 30 mmHg (group B, n = 37); PASP 30-50 mmHg (mild PH; group C, n = 34); and PASP ≥ 50 mmHg (moderate-to-severe PH; group D, n = 31). Longitudinal peak systolic strain (ε) and strain rate (SR), including systolic strain rate (SRs), early diastolic strain rate (SRe) and late diastolic strain rate (SRa) were measured in the basal, middle and apical segments of the right ventricular free wall in participants by two-dimensional speckle tracking echocardiography (2D-STE) from the apical four-chamber view. A p < 0.05 was set for statistical significance. RESULTS: The parameters of ε, SRs, SRe, and SRa were significantly decreased in groups C and D compared with groups A and B. The ε of each segments was significantly lower in group D than in group C, while there were no differences in SRs, SRe and SRa between groups C and D. CONCLUSIONS: Strain and strain rate imaging could early detect the right ventricular dysfunction in SLE patients with PH, and provide important value for clinical therapy and prognosis of these patients. Sociedade Brasileira de Cardiologia - SBC 2018-07 /pmc/articles/PMC6078377/ /pubmed/29898016 http://dx.doi.org/10.5935/abc.20180091 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Luo, Runlan Cui, Hongyan Huang, Dongmei Sun, Lihua Song, Shengda Sun, Mengyao Li, Guangsen Early Assessment of Right Ventricular Function in Systemic Lupus Erythematosus Patients using Strain and Strain Rate Imaging |
title | Early Assessment of Right Ventricular Function in Systemic Lupus
Erythematosus Patients using Strain and Strain Rate Imaging |
title_full | Early Assessment of Right Ventricular Function in Systemic Lupus
Erythematosus Patients using Strain and Strain Rate Imaging |
title_fullStr | Early Assessment of Right Ventricular Function in Systemic Lupus
Erythematosus Patients using Strain and Strain Rate Imaging |
title_full_unstemmed | Early Assessment of Right Ventricular Function in Systemic Lupus
Erythematosus Patients using Strain and Strain Rate Imaging |
title_short | Early Assessment of Right Ventricular Function in Systemic Lupus
Erythematosus Patients using Strain and Strain Rate Imaging |
title_sort | early assessment of right ventricular function in systemic lupus
erythematosus patients using strain and strain rate imaging |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078377/ https://www.ncbi.nlm.nih.gov/pubmed/29898016 http://dx.doi.org/10.5935/abc.20180091 |
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