Orthotopic and heterotopic murine models of pancreatic cancer and their different responses to FOLFIRINOX chemotherapy

Syngeneic, immunocompetent allograft tumor models recapitulate important aspects of the tumor microenvironment and have short tumor latency with predictable growth kinetics, making them useful for trialing novel therapeutics. Here, we describe surgical techniques for orthotopic and heterotopic pancr...

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Detalles Bibliográficos
Autores principales: Erstad, Derek J., Sojoodi, Mozhdeh, Taylor, Martin S., Ghoshal, Sarani, Razavi, Allen A., Graham-O'Regan, Katherine A., Bardeesy, Nabeel, Ferrone, Cristina R., Lanuti, Michael, Caravan, Peter, Tanabe, Kenneth K., Fuchs, Bryan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078400/
https://www.ncbi.nlm.nih.gov/pubmed/29903803
http://dx.doi.org/10.1242/dmm.034793

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