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Regenerating hair cells in vestibular sensory epithelia from humans

Human vestibular sensory epithelia in explant culture were incubated in gentamicin to ablate hair cells. Subsequent transduction of supporting cells with ATOH1 using an Ad-2 viral vector resulted in generation of highly significant numbers of cells expressing the hair cell marker protein myosin VIIa...

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Detalles Bibliográficos
Autores principales:	Taylor, Ruth Rebecca, Filia, Anastasia, Paredes, Ursula, Asai, Yukako, Holt, Jeffrey R, Lovett, Michael, Forge, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Human Biology and Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078492/ https://www.ncbi.nlm.nih.gov/pubmed/30019672 http://dx.doi.org/10.7554/eLife.34817

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