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UGT1A1 promoter polymorphism associated with serum bilirubin level in Saudi patients with sickle cell disease

BACKGROUND AND OBJECTIVES: Polymorphism in (TA)n of the UGT1A1 promoter influences bilirubin level and risk of gallstones in patients with sickle cell disease (SCD) of African descent. Modifiers of bilirubin level and gallstones in Saudi patients with SCD are not known. DESIGN AND SETTINGS: Patients...

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Detalles Bibliográficos
Autores principales: Hamad, Zainab, Aljedai, Abdullah, Halwani, Rabih, AlSultan, Abdulrahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: King Faisal Specialist Hospital and Research Centre 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078505/
https://www.ncbi.nlm.nih.gov/pubmed/24060717
http://dx.doi.org/10.5144/0256-4947.2013.372