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Enhancing T cell therapy through TCR signaling-responsive nanoparticle drug delivery
Adoptive cell therapy (ACT) with antigen-specific T cells has shown remarkable clinical success, but approaches to safely and effectively augment T cell function, especially in solid tumors, remain of great interest. Here we describe a strategy to “backpack” large quantities of supporting protein dr...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078803/ https://www.ncbi.nlm.nih.gov/pubmed/29985479 http://dx.doi.org/10.1038/nbt.4181 |