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Enhancing T cell therapy through TCR signaling-responsive nanoparticle drug delivery

Adoptive cell therapy (ACT) with antigen-specific T cells has shown remarkable clinical success, but approaches to safely and effectively augment T cell function, especially in solid tumors, remain of great interest. Here we describe a strategy to “backpack” large quantities of supporting protein dr...

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Detalles Bibliográficos
Autores principales:	Tang, Li, Zheng, Yiran, de Melo, Mariane Bandeira, Mabardi, Llian, Castaño, Ana P., Xie, Yu-Qing, Li, Na, Kudchodkar, Sagar B., Wong, Hing C., Jeng, Emily K., Maus, Marcela V., Irvine, Darrell J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078803/ https://www.ncbi.nlm.nih.gov/pubmed/29985479 http://dx.doi.org/10.1038/nbt.4181

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