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Closing the Gaps: Endoscopic Suturing for Large Submucosal and Full-Thickness Defects

This article is a systematic review of relevant literature on endoscopic suturing as a primary closure technique for large submucosal and full-thickness defects after endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), and endoscopic full-thickness resection (EFTR). A compreh...

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Autores principales: Kukreja, Keshav, Chennubhotla, Suma, Bhandari, Bharat, Arora, Ankit, Singhal, Shashideep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Gastrointestinal Endoscopy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078935/
https://www.ncbi.nlm.nih.gov/pubmed/29502382
http://dx.doi.org/10.5946/ce.2017.117
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author Kukreja, Keshav
Chennubhotla, Suma
Bhandari, Bharat
Arora, Ankit
Singhal, Shashideep
author_facet Kukreja, Keshav
Chennubhotla, Suma
Bhandari, Bharat
Arora, Ankit
Singhal, Shashideep
author_sort Kukreja, Keshav
collection PubMed
description This article is a systematic review of relevant literature on endoscopic suturing as a primary closure technique for large submucosal and full-thickness defects after endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), and endoscopic full-thickness resection (EFTR). A comprehensive literature search was conducted through 2016 by using PubMed, to find peer-reviewed original articles. The specific factors considered were the procedural indications and details, success rates, clinical outcomes including complications, and study limitations. Six original articles were included in the final review: two with non-human subjects and four with human subjects. The mean success rate of endoscopic suturing was 97.4% (100% for human subjects and 95.4% for non-human subjects). The procedural time ranged from 7 to 89 min. The average size and depth of lesions were 2.71 cm (3.74 cm [human] and 1.96 cm [non-human]) and 1.52 cm, respectively. The technique itself had no reported impact on mortality. In conclusion, endoscopic suturing is a minimally invasive technique for the primary closure of defects caused by EMR, ESD, and EFTR, with a high success and low complication rate.
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spelling pubmed-60789352018-08-08 Closing the Gaps: Endoscopic Suturing for Large Submucosal and Full-Thickness Defects Kukreja, Keshav Chennubhotla, Suma Bhandari, Bharat Arora, Ankit Singhal, Shashideep Clin Endosc Review This article is a systematic review of relevant literature on endoscopic suturing as a primary closure technique for large submucosal and full-thickness defects after endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD), and endoscopic full-thickness resection (EFTR). A comprehensive literature search was conducted through 2016 by using PubMed, to find peer-reviewed original articles. The specific factors considered were the procedural indications and details, success rates, clinical outcomes including complications, and study limitations. Six original articles were included in the final review: two with non-human subjects and four with human subjects. The mean success rate of endoscopic suturing was 97.4% (100% for human subjects and 95.4% for non-human subjects). The procedural time ranged from 7 to 89 min. The average size and depth of lesions were 2.71 cm (3.74 cm [human] and 1.96 cm [non-human]) and 1.52 cm, respectively. The technique itself had no reported impact on mortality. In conclusion, endoscopic suturing is a minimally invasive technique for the primary closure of defects caused by EMR, ESD, and EFTR, with a high success and low complication rate. Korean Society of Gastrointestinal Endoscopy 2018-07 2018-03-05 /pmc/articles/PMC6078935/ /pubmed/29502382 http://dx.doi.org/10.5946/ce.2017.117 Text en Copyright © 2018 Korean Society of Gastrointestinal Endoscopy This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Kukreja, Keshav
Chennubhotla, Suma
Bhandari, Bharat
Arora, Ankit
Singhal, Shashideep
Closing the Gaps: Endoscopic Suturing for Large Submucosal and Full-Thickness Defects
title Closing the Gaps: Endoscopic Suturing for Large Submucosal and Full-Thickness Defects
title_full Closing the Gaps: Endoscopic Suturing for Large Submucosal and Full-Thickness Defects
title_fullStr Closing the Gaps: Endoscopic Suturing for Large Submucosal and Full-Thickness Defects
title_full_unstemmed Closing the Gaps: Endoscopic Suturing for Large Submucosal and Full-Thickness Defects
title_short Closing the Gaps: Endoscopic Suturing for Large Submucosal and Full-Thickness Defects
title_sort closing the gaps: endoscopic suturing for large submucosal and full-thickness defects
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078935/
https://www.ncbi.nlm.nih.gov/pubmed/29502382
http://dx.doi.org/10.5946/ce.2017.117
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