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Ectopic overexpression of Kir6.1 in the mouse heart impacts on the life expectancy

We recently reported the reduced ATP-sensitive potassium (K(ATP)) channel activities in the transgenic mouse heart overexpressing the vascular type K(ATP) channel pore-forming subunit (Kir6.1). Although dysfunction of cardiac K(ATP) channel has been nominated as a cause of cardiomyopathy in human, t...

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Detalles Bibliográficos
Autores principales:	Watanabe, Yasuhiro, Kishimoto, Takashi, Miki, Takashi, Seino, Susumu, Nakaya, Haruaki, Matsumoto, Akio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078942/ https://www.ncbi.nlm.nih.gov/pubmed/30082733 http://dx.doi.org/10.1038/s41598-018-30175-5

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