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Insights into the structure and dynamics of lysyl oxidase propeptide, a flexible protein with numerous partners
Lysyl oxidase (LOX) catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagens and elastin, which is the first step of the cross-linking of these extracellular matrix proteins. It is secreted as a proenzyme activated by bone morphogenetic protein-1, which releases the LOX...
Autores principales: | Vallet, Sylvain D., Miele, Adriana E., Uciechowska-Kaczmarzyk, Urszula, Liwo, Adam, Duclos, Bertrand, Samsonov, Sergey A., Ricard-Blum, Sylvie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078952/ https://www.ncbi.nlm.nih.gov/pubmed/30082873 http://dx.doi.org/10.1038/s41598-018-30190-6 |
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