Cargando…
Inverse-response Ca(2+) indicators for optogenetic visualization of neuronal inhibition
We have developed a series of yellow genetically encoded Ca(2+) indicators for optical imaging (Y-GECOs) with inverted responses to Ca(2+) and apparent dissociation constants (K(d)′) ranging from 25 to 2400 nM. To demonstrate the utility of this affinity series of Ca(2+) indicators, we expressed the...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079023/ https://www.ncbi.nlm.nih.gov/pubmed/30082904 http://dx.doi.org/10.1038/s41598-018-30080-x |