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NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer

Alternative splicing is dysregulated in cancer and the reactivation of telomerase involves the splicing of TERT transcripts to produce full-length (FL) TERT. Knowledge about the splicing factors that enhance or silence FL hTERT is lacking. We identified splicing factors that reduced telomerase activ...

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Detalles Bibliográficos
Autores principales:	Ludlow, Andrew T., Wong, Mandy Sze, Robin, Jerome D., Batten, Kimberly, Yuan, Laura, Lai, Tsung-Po, Dahlson, Nicole, Zhang, Lu, Mender, Ilgen, Tedone, Enzo, Sayed, Mohammed E., Wright, Woodring E., Shay, Jerry W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079032/ https://www.ncbi.nlm.nih.gov/pubmed/30082712 http://dx.doi.org/10.1038/s41467-018-05582-x

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