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Development of an inducible anti-VEGF rAAV gene therapy strategy for the treatment of wet AMD
Vascular endothelial growth factor (VEGF) is a key mediator in the development and progression of choroidal neovascularization (CNV) in patients with wet age-related macular degeneration (AMD). As a consequence, current treatment strategies typically focus on the administration of anti-VEGF agents,...
Autores principales: | Reid, Christopher A., Nettesheim, Emily R., Connor, Thomas B., Lipinski, Daniel M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079038/ https://www.ncbi.nlm.nih.gov/pubmed/30082848 http://dx.doi.org/10.1038/s41598-018-29726-7 |
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