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Chitin promotes antigen-specific Th2 cell-mediated murine asthma through induction of IL-33-mediated IL-1β production by DCs

Chitin, which is a major component of house dust mites (HDM), fungi, crustaceans, etc., can activate immune cells, suggesting that it contributes to development of allergic disorders such as asthma. Although the pathophysiological sensitization route of asthmatic patients to allergens is considered...

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Detalles Bibliográficos
Autores principales:	Arae, Ken, Morita, Hideaki, Unno, Hirotoshi, Motomura, Kenichiro, Toyama, Sumika, Okada, Naoko, Ohno, Tatsukuni, Tamari, Masato, Orimo, Keisuke, Mishima, Yuko, Suto, Hajime, Okumura, Ko, Sudo, Katsuko, Miyazawa, Hiroshi, Taguchi, Haruhiko, Saito, Hirohisa, Matsumoto, Kenji, Nakae, Susumu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079063/ https://www.ncbi.nlm.nih.gov/pubmed/30082755 http://dx.doi.org/10.1038/s41598-018-30259-2

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