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Glucocorticoid receptor promotes the function of myeloid-derived suppressor cells by suppressing HIF1α-dependent glycolysis

Immunomodulatory signaling imposes tight regulations on metabolic programs within immune cells and consequentially determines immune response outcomes. Although the glucocorticoid receptor (GR) has been recently implicated in regulating the function of myeloid-derived suppressor cells (MDSCs), wheth...

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Detalles Bibliográficos
Autores principales: Lu, Yun, Liu, Huanrong, Bi, Yujing, Yang, Hui, Li, Yan, Wang, Jian, Zhang, Zhengguo, Wang, Yu, Li, Chunxiao, Jia, Anna, Han, Linian, Hu, Ying, Zhao, Yong, Wang, Ruoning, Liu, Guangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079089/
https://www.ncbi.nlm.nih.gov/pubmed/28287112
http://dx.doi.org/10.1038/cmi.2017.5