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TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells

Yes-associated protein (YAP), the downstream transducer of the Hippo pathway, is a key regulator of organ size, differentiation and tumorigenesis. To uncover Hippo-independent YAP regulators, we performed a genome-wide CRISPR screen that identifies the transcriptional repressor protein Trichorhinoph...

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Detalles Bibliográficos
Autores principales:	Elster, Dana, Tollot, Marie, Schlegelmilch, Karin, Ori, Alessandro, Rosenwald, Andreas, Sahai, Erik, von Eyss, Björn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079100/ https://www.ncbi.nlm.nih.gov/pubmed/30082728 http://dx.doi.org/10.1038/s41467-018-05370-7

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