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Intracellular and Intercellular Signalling Mechanisms following DNA Damage Are Modulated By PINK1
Impaired mitochondrial function and accumulation of DNA damage have been recognized as hallmarks of age-related diseases. Mitochondrial dysfunction initiates protective signalling mechanisms coordinated at nuclear level particularly by modulating transcription of stress signalling factors. In turn,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079383/ https://www.ncbi.nlm.nih.gov/pubmed/30116473 http://dx.doi.org/10.1155/2018/1391387 |