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The Impact of Type 2 Diabetes Mellitus on Long-Term Prognosis in Patients of Different Ages with Myocardial Infarction

The objective of the study was to assess the impact of DM2 at baseline on long-term mortality after acute myocardial infarction (MI) among different age groups. The data were taken from: “Register of Acute Myocardial Infarction.” A total of 862 patients were followed for five years after acute myoca...

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Autores principales: Afanasiev, S. A., Garganeeva, A. A., Kuzheleva, E. A., Andriyanova, A. V., Kondratieva, D. S., Popov, S. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079422/
https://www.ncbi.nlm.nih.gov/pubmed/30116733
http://dx.doi.org/10.1155/2018/1780683
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author Afanasiev, S. A.
Garganeeva, A. A.
Kuzheleva, E. A.
Andriyanova, A. V.
Kondratieva, D. S.
Popov, S. V.
author_facet Afanasiev, S. A.
Garganeeva, A. A.
Kuzheleva, E. A.
Andriyanova, A. V.
Kondratieva, D. S.
Popov, S. V.
author_sort Afanasiev, S. A.
collection PubMed
description The objective of the study was to assess the impact of DM2 at baseline on long-term mortality after acute myocardial infarction (MI) among different age groups. The data were taken from: “Register of Acute Myocardial Infarction.” A total of 862 patients were followed for five years after acute myocardial infarction. The primary endpoint was death from any cause. The patients were categorized into 2 groups based on their ages: group 1—comprised patients older than working age (n = 358) and group 2—comprised employable patients (n = 504). A total of 208 patients were diagnosed with both cardiovascular disease and DM2. Elderly patients with DM2 had worse prognosis and increased five-year mortality compared with patients of the same age group without DM2. Statistically significant differences in long-term outcomes were found in adult patients (p = 0.004) only in group with longer duration of diabetes, unlike the group with DM2 onset. In conclusion, Type 2 DM increased 5-year mortality rate of elderly patients with myocardial infarction. However, younger patients with both myocardial infarction and DM2 had more complications in the early post-MI period compared with patients of the same age group without DM2 but did not show any statistically significant differences in the long-term outcome.
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spelling pubmed-60794222018-08-16 The Impact of Type 2 Diabetes Mellitus on Long-Term Prognosis in Patients of Different Ages with Myocardial Infarction Afanasiev, S. A. Garganeeva, A. A. Kuzheleva, E. A. Andriyanova, A. V. Kondratieva, D. S. Popov, S. V. J Diabetes Res Research Article The objective of the study was to assess the impact of DM2 at baseline on long-term mortality after acute myocardial infarction (MI) among different age groups. The data were taken from: “Register of Acute Myocardial Infarction.” A total of 862 patients were followed for five years after acute myocardial infarction. The primary endpoint was death from any cause. The patients were categorized into 2 groups based on their ages: group 1—comprised patients older than working age (n = 358) and group 2—comprised employable patients (n = 504). A total of 208 patients were diagnosed with both cardiovascular disease and DM2. Elderly patients with DM2 had worse prognosis and increased five-year mortality compared with patients of the same age group without DM2. Statistically significant differences in long-term outcomes were found in adult patients (p = 0.004) only in group with longer duration of diabetes, unlike the group with DM2 onset. In conclusion, Type 2 DM increased 5-year mortality rate of elderly patients with myocardial infarction. However, younger patients with both myocardial infarction and DM2 had more complications in the early post-MI period compared with patients of the same age group without DM2 but did not show any statistically significant differences in the long-term outcome. Hindawi 2018-07-10 /pmc/articles/PMC6079422/ /pubmed/30116733 http://dx.doi.org/10.1155/2018/1780683 Text en Copyright © 2018 S. A. Afanasiev et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Afanasiev, S. A.
Garganeeva, A. A.
Kuzheleva, E. A.
Andriyanova, A. V.
Kondratieva, D. S.
Popov, S. V.
The Impact of Type 2 Diabetes Mellitus on Long-Term Prognosis in Patients of Different Ages with Myocardial Infarction
title The Impact of Type 2 Diabetes Mellitus on Long-Term Prognosis in Patients of Different Ages with Myocardial Infarction
title_full The Impact of Type 2 Diabetes Mellitus on Long-Term Prognosis in Patients of Different Ages with Myocardial Infarction
title_fullStr The Impact of Type 2 Diabetes Mellitus on Long-Term Prognosis in Patients of Different Ages with Myocardial Infarction
title_full_unstemmed The Impact of Type 2 Diabetes Mellitus on Long-Term Prognosis in Patients of Different Ages with Myocardial Infarction
title_short The Impact of Type 2 Diabetes Mellitus on Long-Term Prognosis in Patients of Different Ages with Myocardial Infarction
title_sort impact of type 2 diabetes mellitus on long-term prognosis in patients of different ages with myocardial infarction
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079422/
https://www.ncbi.nlm.nih.gov/pubmed/30116733
http://dx.doi.org/10.1155/2018/1780683
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