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Inhibition of Proteasome Activity Upregulates IL-6 Expression in RPE Cells through the Activation of P38 MAPKs

PURPOSE: As far as we know, during the development of age-related macular degeneration (AMD), the activity of proteasome in retinal pigment epithelium cells (RPE) gradually decreases. And a lot of research has shown that age-related macular degeneration is closely related to inflammation and autoimm...

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Detalles Bibliográficos
Autores principales: Qin, Tingyu, Gao, Shasha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079444/
https://www.ncbi.nlm.nih.gov/pubmed/30116631
http://dx.doi.org/10.1155/2018/5392432