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Microglia P2X4 receptors as pharmacological targets for demyelinating diseases
Pharmacological activation of the P2X4 receptor expressed by brain microglia may provide a novel avenue to promote remyelination and improve clinical symptoms in experimental autoimmune encephalomyelitis and potentially in multiple sclerosis.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079532/ https://www.ncbi.nlm.nih.gov/pubmed/30037978 http://dx.doi.org/10.15252/emmm.201809369 |
| _version_ | 1783345296125722624 |
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| author | Di Virgilio, Francesco Sarti, Alba Clara |
| author_facet | Di Virgilio, Francesco Sarti, Alba Clara |
| author_sort | Di Virgilio, Francesco |
| collection | PubMed |
| description | Pharmacological activation of the P2X4 receptor expressed by brain microglia may provide a novel avenue to promote remyelination and improve clinical symptoms in experimental autoimmune encephalomyelitis and potentially in multiple sclerosis. |
| format | Online Article Text |
| id | pubmed-6079532 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-60795322018-08-09 Microglia P2X4 receptors as pharmacological targets for demyelinating diseases Di Virgilio, Francesco Sarti, Alba Clara EMBO Mol Med News & Views Pharmacological activation of the P2X4 receptor expressed by brain microglia may provide a novel avenue to promote remyelination and improve clinical symptoms in experimental autoimmune encephalomyelitis and potentially in multiple sclerosis. John Wiley and Sons Inc. 2018-07-23 2018-08 /pmc/articles/PMC6079532/ /pubmed/30037978 http://dx.doi.org/10.15252/emmm.201809369 Text en © 2018 The Authors. Published under the terms of the CC BY 4.0 license This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | News & Views Di Virgilio, Francesco Sarti, Alba Clara Microglia P2X4 receptors as pharmacological targets for demyelinating diseases |
| title | Microglia P2X4 receptors as pharmacological targets for demyelinating diseases |
| title_full | Microglia P2X4 receptors as pharmacological targets for demyelinating diseases |
| title_fullStr | Microglia P2X4 receptors as pharmacological targets for demyelinating diseases |
| title_full_unstemmed | Microglia P2X4 receptors as pharmacological targets for demyelinating diseases |
| title_short | Microglia P2X4 receptors as pharmacological targets for demyelinating diseases |
| title_sort | microglia p2x4 receptors as pharmacological targets for demyelinating diseases |
| topic | News & Views |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079532/ https://www.ncbi.nlm.nih.gov/pubmed/30037978 http://dx.doi.org/10.15252/emmm.201809369 |
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