Changing Paradigm from one Target one Ligand Towards Multi-target Directed Ligand Design for Key Drug Targets of Alzheimer Disease: An Important Role of In Silico Methods in Multi-target Directed Ligands Design

Alzheimer disease (AD) is now considered as a multifactorial neurodegenerative disorder and rapidly increasing to an alarming situation and causing higher death rate. One target one ligand hypothesis does not provide complete solution of AD due to multifactorial nature of the disease and one target...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Akhil, Tiwari, Ashish, Sharma, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080096/
https://www.ncbi.nlm.nih.gov/pubmed/29542413
http://dx.doi.org/10.2174/1570159X16666180315141643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080096/
https://www.ncbi.nlm.nih.gov/pubmed/29542413
http://dx.doi.org/10.2174/1570159X16666180315141643

Ejemplares similares