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Understanding the potential bias of variance components estimators when using genomic models
BACKGROUND: Genomic models that link phenotypes to dense genotype information are increasingly being used for infering variance parameters in genetics studies. The variance parameters of these models can be inferred using restricted maximum likelihood, which produces consistent, asymptotically norma...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080367/ https://www.ncbi.nlm.nih.gov/pubmed/30081816 http://dx.doi.org/10.1186/s12711-018-0411-0 |