Cargando…

New Insights Into Permeation of Large Cations Through ATP-Gated P2X Receptors

The permeability of large cations through the P2X pore has remained arguably the most controversial and complicated topic in P2X-related research, with the emergence of conflicting studies on the existence, mechanism and physiological relevance of a so-called “dilated” state. Due to the important ro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Peverini, Laurie, Beudez, Juline, Dunning, Kate, Chataigneau, Thierry, Grutter, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080412/ https://www.ncbi.nlm.nih.gov/pubmed/30108481 http://dx.doi.org/10.3389/fnmol.2018.00265

Ejemplares similares

Exploring the ATP-binding site of P2X receptors
por: Chataigneau, Thierry, et al.
Publicado: (2013)

P2X-GCaMPs as Versatile Tools for Imaging Extracellular ATP Signaling
por: Ollivier, Matthias, et al.
Publicado: (2021)

P2X2 Dominant Deafness Mutations Have No Negative Effect on Wild-Type Isoform: Implications for Functional Rescue and in Deafness Mechanism
por: Zhu, Yan, et al.
Publicado: (2017)

Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channel
por: Habermacher, Chloé, et al.
Publicado: (2016)

Lateral fenestrations in the extracellular domain of the glycine receptor contribute to the main chloride permeation pathway
por: Cerdan, Adrien H., et al.
Publicado: (2022)

P2X7 Receptors and TMEM16 Channels Are Functionally Coupled with Implications for Macropore Formation and Current Facilitation
por: Dunning, Kate, et al.
Publicado: (2021)

ATP-gated P2X receptors in health and disease
por: Burnstock, Geoffrey, et al.
Publicado: (2014)

Contribution of the Juxtatransmembrane Intracellular Regions to the Time Course and Permeation of ATP-gated P2X7 Receptor Ion Channels
por: Allsopp, Rebecca C., et al.
Publicado: (2015)

The ATP-Gated P2X7 Receptor As a Target for the Treatment of Drug-Resistant Epilepsy
por: Beamer, Edward, et al.
Publicado: (2017)

Permeation and interaction of monovalent cations with the cGMP-gated channel of cone photoreceptors
Publicado: (1992)

Allosteric Effects of Permeating Cations on Gating Currents during K(+) Channel Deactivation
por: Chen, Fred S.P., et al.
Publicado: (1997)

Identification of amino acid residues relevant for gating and permeation of the cation channel TRPC3
por: Schleifer, Hannes, et al.
Publicado: (2008)

Proteomics to Identify Proteins Interacting with P2X2 Ligand-Gated Cation Channels
por: Singh, Harpreet, et al.
Publicado: (2009)

Structural insights into the competitive inhibition of the ATP-gated P2X receptor channel
por: Kasuya, Go, et al.
Publicado: (2017)

Responses of Rat P2X(2) Receptors to Ultrashort Pulses of ATP Provide Insights into ATP Binding and Channel Gating
por: Moffatt, Luciano, et al.
Publicado: (2007)

Voltage- and [ATP]-dependent Gating of the P2X(2) ATP Receptor Channel
por: Fujiwara, Yuichiro, et al.
Publicado: (2009)

Permeation and block by internal and external divalent cations of the catfish cone photoreceptor cGMP-gated channel
Publicado: (1995)

Permeation of internal and external monovalent cations through the catfish cone photoreceptor cGMP-gated channel
Publicado: (1995)

Control of Cation Permeation through the Nicotinic Receptor Channel
por: Wang, Hai-Long, et al.
Publicado: (2008)

Slow permeation of organic cations in acetylcholine receptor channels
Publicado: (1986)

Nonselective cation permeation in an AMPA-type glutamate receptor
por: Biedermann, Johann, et al.
Publicado: (2021)

Delta glutamate receptors are functional glycine- and ᴅ-serine–gated cation channels in situ
por: Carrillo, Elisa, et al.
Publicado: (2021)

Permeation of Large Tetra-Alkylammonium Cations through Mutant and Wild-Type Voltage-Gated Sodium Channels as Revealed by Relief of Block at High Voltage
por: Huang, Chien-Jung, et al.
Publicado: (2000)

A Role of the Fast ATP-gated P2X(1) Cation Channel in Thrombosis of Small Arteries In Vivo
por: Hechler, Béatrice, et al.
Publicado: (2003)

Role of Calcium Permeation in Dihydropyridine Receptor Function: Insights into Channel Gating and Excitation–Contraction Coupling
por: Dirksen, Robert T., et al.
Publicado: (1999)

Identification of a distinct desensitisation gate in the ATP-gated P2X2 receptor
por: Stavrou, Anastasios, et al.
Publicado: (2020)

ATP P2X3 receptors and neuronal sensitization
por: Fabbretti, Elsa
Publicado: (2013)

DIFFUSION AND PERMEATION OF CATIONS IN HUMAN AND DOG ERYTHROCYTES
por: Harris, E. J., et al.
Publicado: (1957)

Generation and Characterization of Specific Monoclonal Antibodies and Nanobodies Directed Against the ATP-Gated Channel P2X4
por: Bergmann, Philine, et al.
Publicado: (2019)

Permeation of both cations and anions through a single class of ATP- activated ion channels in developing chick skeletal muscle
Publicado: (1990)

Architecture of the HCN selectivity filter and control of cation permeation
por: Macri, Vincenzo, et al.
Publicado: (2012)

Primitive ATP-activated P2X receptors: discovery, function and pharmacology
por: Fountain, Samuel J.
Publicado: (2013)

ATP Signaling Controlling Dyskinesia Through P2X7 Receptors
por: Fonteles, Analu A., et al.
Publicado: (2020)

Advances in Ca(V)1.1 gating: New insights into permeation and voltage-sensing mechanisms
por: Bibollet, Hugo, et al.
Publicado: (2023)

Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
por: Sauguet, Ludovic, et al.
Publicado: (2013)

Permeation and interaction of divalent cations in calcium channels of snail neurons
Publicado: (1985)

Divalent Cation Modulation of Ion Permeation in TMEM16 Proteins
por: Nguyen, Dung M., et al.
Publicado: (2021)

Ryanodine Receptor Permeation and Gating: Glowing Cinders That Underlie the Ca(2+) Spark
Publicado: (1999)

The Outer Vestibule of the Na(+) Channel–Toxin Receptor and Modulator of Permeation as Well as Gating
por: Cervenka, René, et al.
Publicado: (2010)

Unmasking coupling between channel gating and ion permeation in the muscle nicotinic receptor
por: Strikwerda, John R, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2opltnstgimmca3vg97j3rtpc1