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Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months
PURPOSE: To study the long-term safety profile and visual outcomes of primary intraocular lens (IOL) implantation in infants <6 months of age. METHODS: This was a retrospective observational study conducted at a tertiary eye care center in South India. Infants under 6 months meeting the selection...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080482/ https://www.ncbi.nlm.nih.gov/pubmed/30038148 http://dx.doi.org/10.4103/ijo.IJO_182_18 |
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author | Negalur, Mithila Sachdeva, Virender Neriyanuri, Srividya Ali, Mohammed Hasnat Kekunnaya, Ramesh |
author_facet | Negalur, Mithila Sachdeva, Virender Neriyanuri, Srividya Ali, Mohammed Hasnat Kekunnaya, Ramesh |
author_sort | Negalur, Mithila |
collection | PubMed |
description | PURPOSE: To study the long-term safety profile and visual outcomes of primary intraocular lens (IOL) implantation in infants <6 months of age. METHODS: This was a retrospective observational study conducted at a tertiary eye care center in South India. Infants under 6 months meeting the selection criteria who underwent cataract surgery (lens aspiration, primary posterior capsulorhexis, and anterior vitrectomy) with primary IOL implantation between January 2008 and December 2011 and minimum 3-year follow-up were included. Patient demographics, serial refractions, visual acuity, complications, and associated amblyopia/strabismus were reviewed. Visual acuity, myopic shift, and complications were the outcome measures. RESULTS: Sixty-nine eyes of 38 infants (31 bilateral; mean age: 4.6 months) were reviewed. Mean follow-up was 51 months (range: 36–84). Median logMAR best-corrected visual acuity at the final visit was 0.74 (interquartile range [IQR]: 0.50–0.98) in eyes with bilateral cataracts and 0.87 (IQR: 0.60–1.14) in eyes with unilateral cataracts with an average myopic shift of 6.7 diopters over 4.2 years. Most common postoperative complication was visual axis opacification (VAO) (13 eyes, 18%), necessitating membranectomy followed by pigmentary IOL deposits (11 eyes, 15%), and IOL decentration and glaucoma in four eyes each (5.6%). Mixed linear effect model found no significant association of age, gender, laterality, and postoperative complications with final visual acuity (P ≥ 0.05). Eyes with unilateral cataracts had a greater myopic shift than bilateral cases (P = 0.03). CONCLUSION: Primary IOL implantation in infants <6 months is reasonably safe in appropriately selected infants. VAO was the most common postoperative complication, and a large myopic shift was observed. |
format | Online Article Text |
id | pubmed-6080482 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-60804822018-08-17 Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months Negalur, Mithila Sachdeva, Virender Neriyanuri, Srividya Ali, Mohammed Hasnat Kekunnaya, Ramesh Indian J Ophthalmol Original Article PURPOSE: To study the long-term safety profile and visual outcomes of primary intraocular lens (IOL) implantation in infants <6 months of age. METHODS: This was a retrospective observational study conducted at a tertiary eye care center in South India. Infants under 6 months meeting the selection criteria who underwent cataract surgery (lens aspiration, primary posterior capsulorhexis, and anterior vitrectomy) with primary IOL implantation between January 2008 and December 2011 and minimum 3-year follow-up were included. Patient demographics, serial refractions, visual acuity, complications, and associated amblyopia/strabismus were reviewed. Visual acuity, myopic shift, and complications were the outcome measures. RESULTS: Sixty-nine eyes of 38 infants (31 bilateral; mean age: 4.6 months) were reviewed. Mean follow-up was 51 months (range: 36–84). Median logMAR best-corrected visual acuity at the final visit was 0.74 (interquartile range [IQR]: 0.50–0.98) in eyes with bilateral cataracts and 0.87 (IQR: 0.60–1.14) in eyes with unilateral cataracts with an average myopic shift of 6.7 diopters over 4.2 years. Most common postoperative complication was visual axis opacification (VAO) (13 eyes, 18%), necessitating membranectomy followed by pigmentary IOL deposits (11 eyes, 15%), and IOL decentration and glaucoma in four eyes each (5.6%). Mixed linear effect model found no significant association of age, gender, laterality, and postoperative complications with final visual acuity (P ≥ 0.05). Eyes with unilateral cataracts had a greater myopic shift than bilateral cases (P = 0.03). CONCLUSION: Primary IOL implantation in infants <6 months is reasonably safe in appropriately selected infants. VAO was the most common postoperative complication, and a large myopic shift was observed. Medknow Publications & Media Pvt Ltd 2018-08 /pmc/articles/PMC6080482/ /pubmed/30038148 http://dx.doi.org/10.4103/ijo.IJO_182_18 Text en Copyright: © 2018 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Negalur, Mithila Sachdeva, Virender Neriyanuri, Srividya Ali, Mohammed Hasnat Kekunnaya, Ramesh Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months |
title | Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months |
title_full | Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months |
title_fullStr | Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months |
title_full_unstemmed | Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months |
title_short | Long-term outcomes following primary intraocular lens implantation in infants younger than 6 months |
title_sort | long-term outcomes following primary intraocular lens implantation in infants younger than 6 months |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080482/ https://www.ncbi.nlm.nih.gov/pubmed/30038148 http://dx.doi.org/10.4103/ijo.IJO_182_18 |
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