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A bioreactor system for the manufacture of a genetically modified Plasmodium falciparum blood stage malaria cell bank for use in a clinical trial

BACKGROUND: Although the use of induced blood stage malaria infection has proven to be a valuable tool for testing the efficacy of vaccines and drugs against Plasmodium falciparum, a limiting factor has been the availability of Good Manufacturing Practice (GMP)—compliant defined P. falciparum strain...

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Detalles Bibliográficos
Autores principales:	Pawliw, Rebecca, Farrow, Rebecca, Sekuloski, Silvana, Jennings, Helen, Healer, Julie, Phuong, Thuan, Sathe, Pri, Pasay, Cielo, Evans, Krystal, Cowman, Alan F., Schofield, Louis, Chen, Nanhua, McCarthy, James, Trenholme, Katharine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080485/ https://www.ncbi.nlm.nih.gov/pubmed/30081913 http://dx.doi.org/10.1186/s12936-018-2435-x

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