Cargando…

miR-145-5p Increases Osteoclast Numbers In Vitro and Aggravates Bone Erosion in Collagen-Induced Arthritis by Targeting Osteoprotegerin

BACKGROUND: Osteoprotegerin (OPG) inhibits bone resorption and binds with strong affinity to receptor activator of NF κB ligand (RANKL), thereby preventing RANKL from binding to its receptor RANK. Osteoclasts have documented effects on bone erosion of rheumatoid arthritis (RA). The aim of this study...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Yaqing, Wang, Xiaoxue, Yang, Mengchen, Ruan, Wendong, Wei, Wei, Gu, Dongmei, Wang, Jing, Guo, Xinling, Guo, Lingxia, Yuan, Yuhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2018
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080580/ https://www.ncbi.nlm.nih.gov/pubmed/30059491 http://dx.doi.org/10.12659/MSM.908219

Ejemplares similares

Fluid Shear Stress Increases Osteocyte and Inhibits Osteoclasts via Downregulating Receptor-Activator of Nuclear Factor κB (RANK)/Osteoprotegerin Expression in Myeloma Microenvironment
por: Wang, Xiaotao, et al.
Publicado: (2019)

Osteoprotegerin Gene (OPG) Polymorphisms Associated with Peri-Implantitis Susceptibility in a Chinese Han Population
por: Zhou, Jian, et al.
Publicado: (2016)

Pediatric Patients with Vitiligo in Eastern China: Abnormalities in 145 Cases Based on Thyroid Function Tests and Immunological Findings
por: Xianfeng, Cheng, et al.
Publicado: (2015)

Continuous Compressive Force Induces Differentiation of Osteoclasts with High Levels of Inorganic Dissolution
por: Matsuike, Rieko, et al.
Publicado: (2019)

Thrombin Aggravates Hypoxia/Reoxygenation Injury of Cardiomyocytes by Activating an Autophagy Pathway-Mediated by SIRT1
por: Wang, Xiaoning, et al.
Publicado: (2021)

Farnesoid X Receptor (FXR) Aggravates Amyloid-β-Triggered Apoptosis by Modulating the cAMP-Response Element-Binding Protein (CREB)/Brain-Derived Neurotrophic Factor (BDNF) Pathway In Vitro
por: Chen, Qingfa, et al.
Publicado: (2019)

β-Arrestin 1/2 Aggravates Podocyte Apoptosis of Diabetic Nephropathy via Wnt/β-Catenin Pathway
por: Wang, Yao, et al.
Publicado: (2018)

MiR-149 Aggravates Pyroptosis in Myocardial Ischemia-Reperfusion Damage via Silencing FoxO3
por: Lin, Jie, et al.
Publicado: (2019)

Adenovirus-Mediated siRNA Targeting CXCR2 Attenuates Titanium Particle-Induced Osteolysis by Suppressing Osteoclast Formation
por: Wang, Chen, et al.
Publicado: (2016)

miR-145-5p Inhibits Vascular Smooth Muscle Cells (VSMCs) Proliferation and Migration by Dysregulating the Transforming Growth Factor-β Signaling Cascade
por: Li, Li, et al.
Publicado: (2018)

The Na+/K+ ATPase Inhibitor Ouabain Attenuates Stemness and Chemoresistance of Osteosarcoma Cells
por: Guo, Weixiong, et al.
Publicado: (2019)

miR-18a Inhibitor Suppresses Leukemia Cell Proliferation by Upregulation of PTEN Expression
por: Zhang, Liping, et al.
Publicado: (2020)

Protective Effect of Hesperidin Against Sepsis-Induced Lung Injury by Inducing the Heat-Stable Protein 70 (Hsp70)/Toll-Like Receptor 4 (TLR4)/ Myeloid Differentiation Primary Response 88 (MyD88) Pathway
por: Yuan, Xiaoyan, et al.
Publicado: (2019)

Paeoniflorin Inhibits Receptor Activator for Nuclear Factor κB (RANK) Ligand-Induced Osteoclast Differentiation In Vitro and Particle-Induced Osteolysis In Vivo
por: Li, Zhuokai, et al.
Publicado: (2018)

MicroRNA-145 Inhibits Cell Migration and Invasion and Regulates Epithelial-Mesenchymal Transition (EMT) by Targeting Connective Tissue Growth Factor (CTGF) in Esophageal Squamous Cell Carcinoma
por: Han, Qiang, et al.
Publicado: (2016)

Gene Modification of Transforming Growth Factor β (TGF-β) and Interleukin 10 (IL-10) in Suppressing Mt Sonicate Induced Osteoclast Formation and Bone Absorption
por: Yi, Lankai, et al.
Publicado: (2018)

Fluid Shear Stress Suppresses Osteoclast Differentiation in RAW264.7 Cells through Extracellular Signal-Regulated Kinase 5 (ERK5) Signaling Pathway
por: Ma, Chongwen, et al.
Publicado: (2020)

Expression of TP53, BCL-2, and VEGFA Genes in Esophagus Carcinoma and its Biological Significance
por: Wei, Wei, et al.
Publicado: (2015)

FTY-720P Suppresses Osteoclast Formation by Regulating Expression of Interleukin-6 (IL-6), Interleukin-4 (IL-4), and Matrix Metalloproteinase 2 (MMP-2)
por: Zhang, Dawei, et al.
Publicado: (2016)

Long Non-Coding RNA (lncRNA) NEAT1 Aggravates Cerebral Ischemia-Reperfusion Injury by Suppressing the Inhibitory Effect of miR-214 on PTEN
por: Shen, Shouyin, et al.
Publicado: (2020)

Bioinformatics Analysis of Gene Expression Profiles for Risk Prediction in Patients with Septic Shock
por: Hu, Yingchun, et al.
Publicado: (2019)

Rho-Associated Protein Kinase (ROCK) Promotes Proliferation and Migration of PC-3 and DU145 Prostate Cancer Cells by Targeting LIM Kinase 1 (LIMK1) and Matrix Metalloproteinase-2 (MMP-2)
por: Gong, Hua, et al.
Publicado: (2019)

A Collagen and Silk Scaffold for Improved Healing of the Tendon and Bone Interface in a Rabbit Model
por: Qian, Shengjun, et al.
Publicado: (2019)

Comparison of Real-Time Two-Dimensional and Three-Dimensional Contrast-Enhanced Ultrasound to Quantify Flow in an In Vitro Model: A Feasibility Study
por: Ruan, Si-Min, et al.
Publicado: (2019)

Caveolin-1 Inhibits Proliferation, Migration, and Invasion of Human Colorectal Cancer Cells by Suppressing Phosphorylation of Epidermal Growth Factor Receptor
por: Yang, Juanli, et al.
Publicado: (2018)

Resveratrol Improves Endothelial Progenitor Cell Function through miR-138 by Targeting Focal Adhesion Kinase (FAK) and Promotes Thrombus Resolution In Vivo
por: Zhang, Yeqing, et al.
Publicado: (2018)

Cervical Cancer Cell Growth, Drug Resistance, and Epithelial-Mesenchymal Transition Are Suppressed by γ-Secretase Inhibitor RO4929097
por: Wang, Lu, et al.
Publicado: (2018)

MicroRNA-106a-3p Induces Apatinib Resistance and Activates Janus-Activated Kinase 2 (JAK2)/Signal Transducer and Activator of Transcription 3 (STAT3) by Targeting the SOCS System in Gastric Cancer
por: Guo, Wei, et al.
Publicado: (2019)

CPNE1 Is a Useful Prognostic Marker and Is Associated with TNF Receptor-Associated Factor 2 (TRAF2) Expression in Prostate Cancer
por: Liang, Jiabei, et al.
Publicado: (2017)

Relationship Between ADAMTS8, ADAMTS18, and ADAMTS20 (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) Expressions and Tumor Molecular Classification, Clinical Pathological Parameters, and Prognosis in Breast Invasive Ductal Carcinoma
por: Guo, Xuhui, et al.
Publicado: (2018)

Aberrant Expression of microRNA-9 Contributes to Development of Intracranial Aneurysm by Suppressing Proliferation and Reducing Contractility of Smooth Muscle Cells
por: Luo, Jing, et al.
Publicado: (2016)

Polymorphism of ABCG2 Gene in Hyperuricemia Patients of Han And Uygur Ethnicity with Phlegm/Non-Phlegm Block in Xinjiang, China
por: Wang, Xianmin, et al.
Publicado: (2018)

Collagen Type X Alpha 1 (COL10A1) Contributes to Cell Proliferation, Migration, and Invasion by Targeting Prolyl 4-Hydroxylase Beta Polypeptide (P4HB) in Breast Cancer
por: Yang, Weibin, et al.
Publicado: (2021)

Lon Peptidase 2, Peroxisomal (LONP2) Contributes to Cervical Carcinogenesis via Oxidative Stress
por: Wu, Wangrong, et al.
Publicado: (2018)

TRAF2 is a Valuable Prognostic Biomarker in Patients with Prostate Cancer
por: Wei, Bingbing, et al.
Publicado: (2017)

Identification of Apolipoprotein C-I Peptides as a Potential Biomarker and its Biological Roles in Breast Cancer
por: Sun, Yadong, et al.
Publicado: (2016)

Overexpression of Epidermal Growth Factor Receptor (EGFR) and HER-2 in Bladder Carcinoma and Its Association with Patients’ Clinical Features
por: Li, Wei, et al.
Publicado: (2018)

Mean Corpuscular Volume Predicts In-Stent Restenosis Risk for Stable Coronary Artery Disease Patients Receiving Elective Percutaneous Coronary Intervention
por: Sun, Lin, et al.
Publicado: (2019)

Berberine Protects Against Palmitate-Induced Apoptosis in Tubular Epithelial Cells by Promoting Fatty Acid Oxidation
por: Sun, Jiye, et al.
Publicado: (2018)

Circular RNA-0001283 Suppresses Breast Cancer Proliferation and Invasion via MiR-187/HIPK3 Axis
por: Hu, Ying, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_m5mn03rujnshkjm6d291j661ce