Synergistic drug combinations from electronic health records and gene expression

Objective: Using electronic health records (EHRs) and biomolecular data, we sought to discover drug pairs with synergistic repurposing potential. EHRs provide real-world treatment and outcome patterns, while complementary biomolecular data, including disease-specific gene expression and drug-protein...

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Detalles Bibliográficos
Autores principales: Low, Yen S, Daugherty, Aaron C, Schroeder, Elizabeth A, Chen, William, Seto, Tina, Weber, Susan, Lim, Michael, Hastie, Trevor, Mathur, Maya, Desai, Manisha, Farrington, Carl, Radin, Andrew A, Sirota, Marina, Kenkare, Pragati, Thompson, Caroline A, Yu, Peter P, Gomez, Scarlett L, Sledge, George W, Kurian, Allison W, Shah, Nigam H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Research and Applications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080645/
https://www.ncbi.nlm.nih.gov/pubmed/27940607
http://dx.doi.org/10.1093/jamia/ocw161

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