Phosphorylation of SNAP-23 at Ser95 causes a structural alteration and negatively regulates Fc receptor–mediated phagosome formation and maturation in macrophages

SNAP-23 is a plasma membrane-localized soluble N-ethylmaleimide–sensitive factor attachment protein receptors (SNARE) involved in Fc receptor (FcR)-mediated phagocytosis. However, the regulatory mechanism underlying its function remains elusive. Using phosphorylation-specific antibodies, SNAP-23 was...

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Detalles Bibliográficos
Autores principales: Sakurai, Chiye, Itakura, Makoto, Kinoshita, Daiki, Arai, Seisuke, Hashimoto, Hitoshi, Wada, Ikuo, Hatsuzawa, Kiyotaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080709/
https://www.ncbi.nlm.nih.gov/pubmed/29771640
http://dx.doi.org/10.1091/mbc.E17-08-0523

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