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BST-2 controls T cell proliferation and exhaustion by shaping the early distribution of a persistent viral infection

The interferon inducible protein, BST-2 (or, tetherin), plays an important role in the innate antiviral defense system by inhibiting the release of many enveloped viruses. Consequently, viruses have evolved strategies to counteract the anti-viral activity of this protein. While the mechanisms by whi...

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Detalles Bibliográficos
Autores principales: Urata, Shuzo, Kenyon, Elizabeth, Nayak, Debasis, Cubitt, Beatrice, Kurosaki, Yohei, Yasuda, Jiro, de la Torre, Juan C., McGavern, Dorian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080785/
https://www.ncbi.nlm.nih.gov/pubmed/30028868
http://dx.doi.org/10.1371/journal.ppat.1007172

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