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Upregulation of miR-370 and miR-543 is associated with reduced expression of heat shock protein 40 in spinocerebellar ataxia type 3

Molecular chaperones are important regulators of protein folding and proteasomal removal of misfolded proteins. In spinocerebellar ataxia type 3 (SCA3), the co-chaperone DnaJ homology subfamily B member 1 (DNAJB1 or heat shock protein 40) is recruited to protein aggregates formed by the disease-caus...

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Detalles Bibliográficos
Autores principales:	Evert, Bernd O., Nalavade, Rohit, Jungverdorben, Johannes, Matthes, Frank, Weber, Stephanie, Rajput, Ashish, Bonn, Stefan, Brüstle, Oliver, Peitz, Michael, Krauß, Sybille
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080806/ https://www.ncbi.nlm.nih.gov/pubmed/30086154 http://dx.doi.org/10.1371/journal.pone.0201794

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